Analysis of cytolytic capability of Natural killer cells and Cytotoxic T cells in the peripheral blood of cancer patients: Thesis Abstract

Document Type : Essay Abstract

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Zoology department - faculty of science- Alazhar university

Abstract

Thesis Abstract
Lung cancer is a one of the most cancer types spreaded worldwide. In Egypt, lung cancer counted as the third cause of deaths among males after liver and bladder cancers. Lung cancer characterized with two type's SCLC represents about (10% to 15%) and NSCLCs which represents (80% to 85%). In NSCLCs, treatment only treat15%–30% of patients due to the presence of tumor mediators which enhance tumor surveillance by secreting PGE2, TGF-β. CD8+ and NK are the main cells to defeat and kill cancer cells. The aim of this study is to address the functionality of T-cells and NK cells on lung cancer patient's pre and post stimulation in-vitro.
Lung cancer is a one of the most cancer types spreaded worldwide. In Egypt, lung cancer counted as the third cause of deaths among males after liver and bladder cancers. Lung cancer characterized with two type's SCLC represents about (10% to 15%) and NSCLCs which represents (80% to 85%). In NSCLCs, treatment only treat15%–30% of patients due to the presence of tumor mediators which enhance tumor surveillance by secreting PGE2, TGF-β. CD8+ and NK are the main cells to defeat and kill cancer cells. The aim of this study is to address the functionality of T-cells and NK cells on lung cancer patient's pre and post stimulation in-vitro.
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Egyptian Journal of Cancer and Biomedical Research
Volume 5, Issue 1.1 - Serial Number 1
Special Issue: Thesis Abstracts
May 2021
Pages 13-13

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