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International Journal of Cancer and Biomedical Research
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abdelmabood, S., Sheta, H., Abdelmaksoud, S., Refky, B., Abo Touk, N., Harb, D., Darwish, A. (2021). Wilms' tumor may be a rare presentation of ovarian neoplasms in girls. International Journal of Cancer and Biomedical Research, 5(3), 87-93. doi: 10.21608/jcbr.2021.49736.1094
Suzy abdelmabood; Heba Sheta; Sherif Abdelmaksoud; Basel Refky; Niveen Abo Touk; Dina Harb; Ahmad Darwish. "Wilms' tumor may be a rare presentation of ovarian neoplasms in girls". International Journal of Cancer and Biomedical Research, 5, 3, 2021, 87-93. doi: 10.21608/jcbr.2021.49736.1094
abdelmabood, S., Sheta, H., Abdelmaksoud, S., Refky, B., Abo Touk, N., Harb, D., Darwish, A. (2021). 'Wilms' tumor may be a rare presentation of ovarian neoplasms in girls', International Journal of Cancer and Biomedical Research, 5(3), pp. 87-93. doi: 10.21608/jcbr.2021.49736.1094
abdelmabood, S., Sheta, H., Abdelmaksoud, S., Refky, B., Abo Touk, N., Harb, D., Darwish, A. Wilms' tumor may be a rare presentation of ovarian neoplasms in girls. International Journal of Cancer and Biomedical Research, 2021; 5(3): 87-93. doi: 10.21608/jcbr.2021.49736.1094

Wilms' tumor may be a rare presentation of ovarian neoplasms in girls

Article 9, Volume 5, Issue 3, September 2021, Page 87-93  XML PDF (26.56 MB)
Document Type: Case Report
DOI: 10.21608/jcbr.2021.49736.1094
Authors
Suzy abdelmabood1; Heba Sheta email orcid 2; Sherif Abdelmaksoud3; Basel Refky4; Niveen Abo Touk5; Dina Harb6; Ahmad Darwish1
1Pediatric Hematology and Oncology Unit, Department of Pediatrics, Faculty of Medicine, Mansoura University, Egypt.
2Pathology Department, Faculty of Medicine, Mansoura University, Egypt.
3Pediatric Surgery Department, Faculty of Medicine, Mansoura University. Egypt.
4Surgical Oncology Department, Faculty of Medicine, Mansoura University, Egypt.
5Clinical Oncology and Nuclear medicine Department, Faculty of Medicine, Mansoura University, Egypt.
6Radiology Department, Faculty of Medicine, Mansoura University, Egypt.
Abstract
Extrarenal Wilms' tumor is a rare malignant disorder. It represents 0.5-1% of Wilms' tumor. Management for ERWT is challenging regarding its pathological diagnosis, staging, treatment and prognosis. Here we report a 4 years old girl, presented with huge pelvi abdominal mass originating from the left ovary which was seen by radiologic assessment as a large lobulated heterogeneously enhancing mixed solid and cystic retroperitoneal mass away from both kidneys, occupying most of the abdomen with pelvic extension; it was displacing bowel loops and pancreas, measuring 13 x 15 x 16 cm without evidence of enlarged lymphadenopathy. The mass was diagnosed postoperatively as an extrarenal Wilms' tumor proved by immunohistochemical staining for Wilms' Tumor1 (WT1) with the negative reaction for other markers that exclude other diagnostic possibilities. The patient had an aggressive presentation and advanced disease. The diagnosis was difficult due to the lack of specific radiologic stigmata and aberrant origin. She was treated with aggressive chemotherapy to suit the advanced stage of her disease and unfavorable histology pattern.
Keywords
Wilms; ovary; aggressive
Main Subjects
Cell-based therapy against cancer
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