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International Journal of Cancer and Biomedical Research
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El-Naggar, S., Arafa, S., Mahmoud, H., Abdel-Halim, K., Hassona, G., Gebril, A., Nady, R., Zidan, A., Salem, M., Alkhazendar, A. (2018). Proteomics applications in biomedical research and diagnosis by luminex in Egypt. International Journal of Cancer and Biomedical Research, 2(3), 20-28. doi: 10.21608/jcbr.2019.34750
Sabry A. El-Naggar; Samah Arafa; Heba A. Mahmoud; Khaled Y. Abdel-Halim; Ghehad Hassona; ara Gebril; Rehab Nady; Abel-Aziz A. Zidan; Mohamed L. Salem; Abdelhalim A. Alkhazendar. "Proteomics applications in biomedical research and diagnosis by luminex in Egypt". International Journal of Cancer and Biomedical Research, 2, 3, 2018, 20-28. doi: 10.21608/jcbr.2019.34750
El-Naggar, S., Arafa, S., Mahmoud, H., Abdel-Halim, K., Hassona, G., Gebril, A., Nady, R., Zidan, A., Salem, M., Alkhazendar, A. (2018). 'Proteomics applications in biomedical research and diagnosis by luminex in Egypt', International Journal of Cancer and Biomedical Research, 2(3), pp. 20-28. doi: 10.21608/jcbr.2019.34750
El-Naggar, S., Arafa, S., Mahmoud, H., Abdel-Halim, K., Hassona, G., Gebril, A., Nady, R., Zidan, A., Salem, M., Alkhazendar, A. Proteomics applications in biomedical research and diagnosis by luminex in Egypt. International Journal of Cancer and Biomedical Research, 2018; 2(3): 20-28. doi: 10.21608/jcbr.2019.34750

Proteomics applications in biomedical research and diagnosis by luminex in Egypt

Reviewers, Volume 2, Issue 3 - Serial Number 4, December 2018, Page 20-28  XML PDF (386.36 K)
DOI: 10.21608/jcbr.2019.34750
Authors
Sabry A. El-Naggarorcid 1; Samah Arafa2; Heba A. Mahmoud3; Khaled Y. Abdel-Halim4; Ghehad Hassona5; ara Gebril6; Rehab Nady7; Abel-Aziz A. Zidan8; Mohamed L. Salemorcid 5; Abdelhalim A. Alkhazendarorcid 5
1Zoology Department, Faculty of Science, Tanta University, Tanta 3111, Egypt
2Pesticides Department, Faculty of Agriculture, Menoufia University, Egypt
3Pharmacology department, Faculty of Medicine, Tanta University.
4Mammalian & Aquatic Toxicology Department, Central Agricultural Pesticides Laboratory, Agricultural Research Center (ARC), Dokki, 12618, Giza, Egypt
5Zoology Department, Faculty of Science, Tanta University
6Division of Biochemistry, Department of Chemistry, Faculty of science, Mansoura University, Dakahlia, Egypt
7Zoology Department, Faculty of Science, Beni Suef University, Egypt
8Zoology Department, Faculty of Science, Damanhur University Zoology Department, Faculty of Science, Tanta
Abstract
To accurate prognosis, diagnosis and treatment for several diseases such as cancer, diabetes and autoimmune diseases, the results of analysis should be accurate with high precision. Luminex is a one of these technologies that able to give accurate results. So far, luminex is not widely distributed in Egypt or other Arabic countries; however, it is widely used in European countries and United States of America. In Egypt, there are almost 18 instrument distributed all over the country. This instrument is mainly used for protein (proteomics) and nucleic acids analysis. The principle of luminex is to use two lasers that detect micro beads of polystyrene set (5.6 µm) or beads of magnetic set (6.5 µm). In this review, we are introducing some new information about luminex technology and its applications in diagnosis and research in different scientific centers in Egypt
Keywords
applications; Cancer; Egypt; luminex; multiplexing; proteomics
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