Proteomics applications in biomedical research and diagnosis by luminex in Egypt

Reviewers

Authors

1 Zoology Department, Faculty of Science, Tanta University, Tanta 3111, Egypt

2 Pesticides Department, Faculty of Agriculture, Menoufia University, Egypt

3 Pharmacology department, Faculty of Medicine, Tanta University.

4 Mammalian & Aquatic Toxicology Department, Central Agricultural Pesticides Laboratory, Agricultural Research Center (ARC), Dokki, 12618, Giza, Egypt

5 Zoology Department, Faculty of Science, Tanta University

6 Division of Biochemistry, Department of Chemistry, Faculty of science, Mansoura University, Dakahlia, Egypt

7 Zoology Department, Faculty of Science, Beni Suef University, Egypt

8 Zoology Department, Faculty of Science, Damanhur University Zoology Department, Faculty of Science, Tanta

Abstract

To accurate prognosis, diagnosis and treatment for several diseases such as cancer, diabetes and autoimmune diseases, the results of analysis should be accurate with high precision. Luminex is a one of these technologies that able to give accurate results. So far, luminex is not widely distributed in Egypt or other Arabic countries; however, it is widely used in European countries and United States of America. In Egypt, there are almost 18 instrument distributed all over the country. This instrument is mainly used for protein (proteomics) and nucleic acids analysis. The principle of luminex is to use two lasers that detect micro beads of polystyrene set (5.6 µm) or beads of magnetic set (6.5 µm). In this review, we are introducing some new information about luminex technology and its applications in diagnosis and research in different scientific centers in Egypt

Keywords